This review article explores the utility of self-collected dry swabs for primary Human Papillomavirus (HPV) screening, a critical method for cervical cancer prevention. It synthesizes current evidence on clinical performance, laboratory considerations, and patient preferences for this screening approach. The article highlights that self-collection methods, particularly with dry swabs, offer a promising alternative to traditional clinician-collected samples, potentially increasing screening participation and accessibility. It details the diagnostic accuracy of various dry swab types and discusses the logistical challenges and advantages for laboratories. Patient perspectives on comfort and convenience are also evaluated, underscoring the potential for improved screening uptake.
Key note: Self-collected dry swabs provide an effective and preferred method for primary HPV screening, enhancing accessibility and participation in cervical cancer prevention programs.