Bartonella-associated glomerulonephritis without endocarditis in a renal transplant recipient

September 1, 2025
Bacteriology
Grace A. Schaack, Rene Bulnes, Deborah Jebakumar, Allen R. Hendricks, Andrew E. Clark
Pathogen:Bartonella
Infection Type:Glomerulonephritis
Pathogen Type:Bacteria

Summary

This case report details a renal transplant recipient who developed glomerulonephritis due to Bartonella infection, notably without the typical presentation of endocarditis. The patient's immunocompromised state likely contributed to this unusual manifestation. Diagnosis required a high degree of clinical suspicion and specific diagnostic methods to identify Bartonella as the causative agent. This highlights the diagnostic challenges of Bartonella-associated glomerulonephritis in transplant patients, where traditional signs may be absent. Early and accurate diagnosis is crucial for effective treatment and preventing severe renal complications in this vulnerable population.

Key note: Bartonella can cause glomerulonephritis in immunocompromised patients without endocarditis, requiring vigilance for atypical presentations.

DOI: 10.1128/asmcr.00092-25