An adult patient with AIDS presented with recurrent meningitis caused by Salmonella arizonae. The diagnosis was confirmed through next-generation sequencing analysis, highlighting the utility of advanced molecular techniques in identifying unusual pathogens, especially in immunocompromised individuals. This case illustrates a rare manifestation of S. arizonae infection, which typically causes gastroenteritis but can lead to severe extra-intestinal disease like meningitis in patients with compromised immune systems. The recurrent nature emphasizes the challenges in managing such infections.
Key note: Next-generation sequencing is crucial for accurate identification of atypical pathogens in complex clinical scenarios.