An immunocompromised adult in Australia presented with acute flaccid myelitis (AFM). The patient's clinical presentation involved neurological deficits characteristic of AFM. Diagnostic methods, likely involving molecular testing of cerebrospinal fluid or respiratory samples, identified Enterovirus D68 (EV-D68) as the causative pathogen. This particular EV-D68 strain was phylogenetically linked to 2018 AFM outbreaks in the USA and documented 2022 cases in France, highlighting its global prevalence and potential for severe neurological complications, especially in vulnerable populations. This case underscores the importance of considering EV-D68 in AFM differential diagnoses, even in immunocompromised adults.
Key note: EV-D68 can cause AFM in immunocompromised adults, with strains showing global epidemiological links.