Mycobacterium abscessus research: learning from challenges

February 4, 2026
Review
Treen RZ,Gonzalez-Juarrero M,Jackson M,Lapierre P,Kremer L,Ghosh P,Ojha AK
Pathogen:Mycobacterium abscessus
Infection Type:Mycobacterial infection
Pathogen Type:Bacteria

Summary

This article focuses on Mycobacterium abscessus (Mab), a rapidly growing mycobacterial species posing a significant public health concern due to its intrinsic and acquired multi-antibiotic resistance. The rising incidence of treatment-refractory Mab infections has spurred intensive research efforts to understand its pathogenesis and develop effective therapeutic strategies. Challenges in treating Mab infections highlight the urgent need for novel antimicrobial agents and improved diagnostic methods. The article emphasizes learning from these challenges to advance research into new treatment modalities and better patient outcomes.

Key note: The increasing prevalence of drug-resistant Mycobacterium abscessus infections necessitates focused research into novel therapies and diagnostic advancements.

DOI: 10.1128/jb.00436-25