The Brief Case: Incidental finding of a liver fluke following resection of hepatocellular carcinoma

January 31, 2025
Case Report
Matthew Chung Yi Koh, Kevin Mong Sheng Sim, Blaine A Mathison, Richard S Bradbury, Jinghao Nicholas Ngiam, Nicholas Jian Hao Chan, Jolene Ee Ling Oon, Aileen Wee, Gabriel Zherong Yan
Pathogen:Clonorchis sinensis
Infection Type:Liver fluke infection
Pathogen Type:Parasite

Summary

A 56-year-old male, with a history of chronic hepatitis B and hepatocellular carcinoma, underwent a partial hepatectomy. Post-surgery, histological examination of the resected liver tissue unexpectedly revealed a liver fluke, identified as Clonorchis sinensis, within the bile duct. The patient had no prior symptoms indicative of parasitic infection, and the diagnosis was an incidental finding during cancer resection. This case highlights the importance of thorough histopathological examination of resected tissues, as parasitic infections can be asymptomatic and coexist with other pathologies, potentially impacting patient management and public health surveillance. The finding underscores the need for vigilance in endemic areas.

Key note: Incidental histopathological findings can uncover asymptomatic parasitic infections coexisting with other diseases.

DOI: 10.1016/S24681253(17)30111-5